Am I taking too many medications?
Medications can improve the lives of people who suffer from chronic conditions, such as diabetes, high blood pressure, high cholesterol, cancer, mental illness and chronic pain. However, taking too many prescription medications can be risky.
Taking more than five medications is called polypharmacy. The risk of harmful effects, drug interactions and hospitalizations increase when you take more medications.
About 3 out of 5 Canadians (65%) aged 65 and older take at least 5 different prescription medications.
About 1 out of 4 Canadians (26%) aged 65 and older take at least 10 different prescription medications. (CIHI 2023)
Always check with your doctor, pharmacist or nurse before changing or stopping any of your medications.
Harmful effects of medication can include:
Hospitalizations
Premature loss of independence
Who is most at risk of harmful effects of medication?
1. People with multiple chronic conditions
People with multiple chronic conditions often take lots of medications to manage each disease. Taking lots of medications for multiple chronic conditions, increases the risk of harmful effects because of:
Drug-drug interactions: medications may have unpredictable effects when they interact with each other.
Drug-disease interactions: medications may have unpredictable effects on another disease a person has.
Sometimes, additional medications are prescribed to counteract the harmful effects of existing medications, which can exacerbate the problem. This is called the prescribing cascade.
2. Women
Women are at greater risk of being prescribed potentially harmful medications, and are more likely to experience their negative side effects.
This is because:
Women have a longer life expectancy, which means they may spend more years taking medications.
Women tend to be diagnosed with more chronic conditions, which leads to more prescriptions.
Women’s bodies process medications differently, which can make some medications stay in the body longer or make their side effects more pronounced.
3. People over the age of 65
People over the age of 65 often manage multiple chronic conditions and take multiple medications to control their symptoms.
Unfortunately, among seniors, harmful effects of medications are reported to be the cause of up to 1 in 3 (30%) hospitalizations (Cosgrave and al. 2025).
This is because, as we get older:
The brain becomes more sensitive to drug effects
Medications stay longer in our body because we have less muscle and more body fat
Our liver and kidneys do not process medications as efficiently as when we were younger
Our body contains less water and medications can become more concentrated
What can I do?
Read these two articles that detail safety tips on how to manage your medications:
9 Quick Safety Tips to Manage Your Medications
5 (More) Quick Safety Tips to Manage Your Medications
Read more strategies to safely manage your medications